Hydroxypropyl-Beta-Cyclodextrin CAS 94035-02-6
Basic Info
Model NO. | Pharm002 |
Transport Package | as Required |
Specification | 25kg/Drum, DRUM, Aluminum Foil Bag |
Trademark | ALLRIGHT G. C. |
Origin | Shandong |
Production Capacity | 60000 Kilogram/Kilograms Per Month |
Product Description
Introduction
Hydroxypropyl-beta-cyclodextrin: Hydroxypropyl beta-cyclodextrin are purified polydisperse products resulting from the controlled reaction of propylene oxide and native beta-cyclodextrin. Hydroxypropyl beta-cyclodextrin is itself very soluble in water (greater than 500 mg/ml at room temperature compared to 18 mg/ml for beta-cyclodextrin), and is used for molecular encapsulation of a variety of sparingly water compounds to enhance the aqueous solubility of the encapsulated compound.
Other Name: beta-Cyclodextrin 2-hydroxypropyl ethers; HPBCD; HPCD
M.W. :1431-1806
Standards: USP38,EP8.4,BP2015,CP2015
Storage:Preserved in well-closed containers
Shelf life : 2 years when properly stored.
Package:1kg/bag,25kg/drum.Or it's at your option .
Function
Hydroxypropyl beta cyclodextrin is a solution to insoluble or low solubility drugs(including plant extracts).Through molecular encapsulation,it could increase the drug solubility and control the release rate of the drug,increase the drug's bioavailability and reduce the toxic side-effets.
1. Suitable for parenteral use, syrups, solutions and oral suspensions as well as for dry formulations (with possibility of in-situ encapsulation).
2. To increase water solubility of poorly soluble drugs.
3. To increase bioavailability.
4. To improve organoleptic properties of bitter or unpleasant actives.
Specification
Item | Index | Testing Results |
Appearance | White crystalline powder, non-toxic, odorless, sweet | Conform |
Content | ≥98% | 99.8%n |
Degree of substitution | 3-10 | 5(or as per customer requirement) |
Propylene Oxide | ≤1ppm | Conform |
Loss on drying | ≤10.0% | 4.6% |
Heavy metal | ≤20ppm | <20ppm |
Arsenic | ≤0.0002% | confirm |
The total number of germ | ≤1000 | Conform |
The total number of mould | ≤100 | Conform |
Pathogenic bacteria | ≤none | Conform |